Endometrial carcinoma: ESMO clinical recommendations for diagnosis, treatment and follow-up.

The diagnosis of endometrial carcinoma requires histopathological confirmation. This diagnosis is made according to the WHO pathological classification. About 80% of endometrial carcinomas are of endometrioid type. Serous (5–10%), clear cell (1–5%), mucinous, mixed, squamous cell, transitional cell and undifferentiated carcinomas are other established subtypes. Endometrial carcinosarcoma is now considered a special, poor-prognosis subtype of endometrial carcinoma.